US · FULC
Fulcrum Therapeutics, Inc.
- Sector
- Healthcare · Biotechnology
- Headquarters
- Cambridge, MA 02139
- Website
- fulcrumtx.com
Price · as of 2025-12-31
$7.36
Market cap 453.45M
Valuation summary
Four models, one snapshot. Upside is target ÷ current − 1.
| Valuation method | Value, $ | Upside, % |
|---|---|---|
| Artificial Intelligence(AI) | $46.26 | +528.53% |
| Intrinsic Value(DCF) | — | — |
| Graham-Dodd Method(GD) | — | — |
| Graham Formula(GF) | — | — |
Valuation history
Annual price (USD per share) overlaid with each model's fair value. Y-axis is log scale.
| Year | Price | AI | DCF | Graham-Dodd | Graham Formula |
|---|---|---|---|---|---|
| 2011 | |||||
| 2012 | |||||
| 2013 | |||||
| 2014 | |||||
| 2015 | |||||
| 2016 | |||||
| 2017 | |||||
| 2018 | |||||
| 2019 | $17.60 | ||||
| 2020 | $12.22 | ||||
| 2021 | $16.01 | $35.88 | $3.36 | $0.00 | $0.00 |
| 2022 | $4.51 | $24.37 | $1.62 | $0.00 | $136.65 |
| 2023 | $11.08 | $29.55 | $1.77 | $0.00 | $71.83 |
| 2024 | $3.14 | $416.59 | $2,326.81 | $3.14 | $0.00 |
| 2025 | $7.81 | $46.26 |
AI valuation
Our deep-learning model estimates Fulcrum Therapeutics, Inc.'s (FULC) per-share fair value from quarterly fundamentals, sector trend, and historical valuation patterns.
- AI fair value
- $46.26
- Current price
- $7.36
- AI upside
- +528.53%
Methodology and confidence bands appear in the dedicated valuation theory section. The AI score is an estimate, not a recommendation.
Intrinsic value (DCF)
Open DCF calculatorThree textbook valuation models, recomputed daily from the latest financial statements. The DCF uses our Chepakovich model. Graham-Dodd and Graham Formula are conservative reference points.
DCF
—
— upside
Graham-Dodd
—
— upside
Graham Formula
—
— upside
Peer comparison
Same-industry comparables, ranked by market cap.
| Basic Info | Model Valuation | Core Valuation | Profitability | Leverage & Liquidity | Growth | Cash Flow | Dividends | Enterprise Value | Risk | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ticker | Company Name | Price | Market Cap | AI Upside | DCF Upside | GD Upside | GF Upside | P/E | P/B | P/S | EV/EBITDA | PEG | P/TBV | Gross Margin | Operating Margin | Net Margin | ROE | ROIC | ROA | Debt/Equity | Interest Coverage | Current Ratio | Quick Ratio | Net Debt/EBITDA | EPS Growth | Sales Growth | FCF Growth | FCF Yield | Op Cash Flow Ratio | Cash ROIC | Dividend Yield | Dividend Payout | Shareholder Yield | EV/EBIT | EV/FCF | EV/Sales | Altman Z-Score |
| FULC | Fulcrum Therapeutics, Inc… | $7.36 | 453.45M | +529% | — | — | — | -6.61 | 1.42 | — | -2.03 | -1.04 | 1.42 | 0.00% | — | — | -25.30% | -1230.41% | -23.89% | 0.02 | — | 27.40 | 27.00 | 2.60 | 63750.00% | -10000.00% | 231903.00% | -12.20% | -4.60 | -876.39% | 0.00% | 0.00% | 28.60% | -1.76 | -2.47 | — | 15.27 |
| ADCT | ADC Therapeutics S.A. | $4.10 | 507.9M | +465% | -82% | — | — | -1.13 | -0.88 | 2.52 | -0.50 | — | -0.88 | 91.60% | -184.44% | -222.83% | 89.97% | 41.28% | -46.65% | -0.61 | -2.60 | 3.82 | 3.37 | 1.25 | -4490.00% | 184.00% | 230.00% | -69.75% | -1.54 | 39.40% | 0.00% | 0.00% | 0.00% | -0.39 | -0.41 | 0.72 | -6.56 |
| BCYC | Bicycle Therapeutics plc | $5.73 | 397.02M | +373% | +110% | — | — | -3.52 | 0.75 | 16.88 | 1.67 | — | 0.75 | -390.34% | -594.96% | -479.18% | -29.04% | 217.72% | -21.78% | 0.01 | -121.31 | 13.81 | 13.61 | 5.28 | -4291.00% | 3076.00% | 16112.00% | -27.87% | -2.45 | 177.02% | 0.00% | 0.00% | 65.25% | 1.31 | 1.65 | -7.78 | 1.58 |
| CMPX | Compass Therapeutics, Inc… | $5.65 | 781.32M | — | — | — | — | -7.47 | 2.95 | 433.91 | -4.53 | -82.17 | 2.95 | 100.00% | -6661.76% | -5808.82% | -36.07% | -3833.78% | -33.22% | 0.05 | — | 14.96 | 14.28 | 0.67 | 909.00% | — | 1046.00% | -12.17% | -5.05 | -3039.88% | 0.00% | 0.00% | 3.89% | -4.39 | -5.54 | 292.63 | 10.68 |
| LXRX | Lexicon Pharmaceuticals, … | $1.47 | 581.34M | +24,271% | +1,124% | — | — | -0.62 | 0.86 | 4.02 | 0.03 | — | 1.23 | 98.02% | -634.20% | -644.78% | -167.66% | -865.73% | -75.93% | 0.74 | -12.65 | 5.44 | 5.34 | -0.23 | -2125.00% | 248148.00% | 1074.00% | -144.07% | -3.95 | -789.72% | 0.00% | 0.00% | 34.92% | 0.02 | 0.03 | -0.15 | -10.01 |
| NGNE | Neurogene Inc. | $23.49 | 363.86M | — | -49% | — | — | -4.04 | 0.98 | 328.17 | -0.05 | -7.88 | 0.98 | -251.03% | -8930.27% | -8123.68% | -30.28% | -1064.50% | -26.92% | 0.04 | -6883.75 | 20.84 | 20.65 | 1.73 | 5124.00% | — | 3801.00% | -23.52% | -4.66 | -920.24% | 0.00% | 0.00% | 0.00% | -0.04 | -0.05 | 3.87 | 6.36 |
| NMRA | Neumora Therapeutics, Inc… | $3.49 | 583.14M | — | — | — | — | -0.97 | 0.83 | — | 0.26 | -36.29 | 0.83 | 0.00% | — | — | -64.48% | -31666.35% | -59.96% | 0.01 | — | 10.51 | 10.29 | 0.53 | 268.00% | — | 1196.00% | -77.03% | -6.12 | -21987.50% | 0.00% | 0.00% | 0.00% | 0.26 | 0.37 | — | -1.09 |
| OCGN | Ocugen, Inc. | $1.82 | 595.72M | +1,481% | -87% | — | +155% | -3.06 | 5.58 | 40.77 | -2.64 | — | 5.58 | 51.47% | -1350.36% | -1333.02% | -154.01% | -938.91% | -73.55% | 1.10 | — | 2.86 | 2.71 | 0.49 | -2308.00% | -3282.00% | -3723.00% | -27.54% | -1.95 | -780.64% | 0.00% | 0.00% | 0.00% | -2.54 | -3.06 | 34.35 | -5.46 |
| OMER | Omeros Corporation | $12.05 | 854.35M | — | — | — | — | -2.84 | -2.44 | — | -3.58 | -6.51 | -2.44 | 0.00% | — | — | 151.08% | -341.82% | -47.86% | -1.13 | -6.86 | 1.69 | 1.60 | -1.30 | 4362.00% | — | -30050.00% | -33.43% | -1.87 | -300.85% | 0.00% | 0.00% | 36.52% | -3.32 | -3.78 | — | -5.80 |
| RAPT | RAPT Therapeutics, Inc. | $57.98 | 958.84M | — | — | — | — | -0.35 | 0.24 | — | 1.34 | -7.75 | 0.24 | 0.00% | — | — | -77.09% | 654.65% | -62.79% | 0.02 | — | 4.87 | 4.78 | 1.22 | 458.00% | — | -1503.00% | -181.11% | -1.72 | 401.25% | 0.00% | 0.00% | 270.67% | 1.33 | 2.16 | — | -3.97 |
About Fulcrum Therapeutics, Inc.
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy; and FTX-6058, an investigational oral fetal hemoglobin inducer for the treatment of sickle cell disease and other hemoglobinopathies, including beta-thalassemia. The company is also discovering drug targets for the treatments of rare neuromuscular, muscular, central nervous system, and hematologic disorders, as well as cardiomyopathies and pulmonary diseases. Fulcrum Therapeutics, Inc. has research and discovery collaboration agreement with Acceleron Pharma Inc. to identify biological targets to modulate specific pathways associated with a targeted indication within the pulmonary disease space; and has a strategic collaboration and license agreement with MyoKardia, Inc. to discover, develop, and commercialize novel targeted therapies for the treatment of genetic cardiomyopathies. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
- CEO
- Alexander C. Sapir
- Employees
- 45
- Beta
- 3.18
Disclaimer: Information on this page is provided for educational purposes only and does not constitute investment advice. Upside computed as (— ÷ $7.36) − 1 = — (DCF, example).